Table 1 Baseline demographic, clinical and neuropsychological characteristics of PD-MCI patients considered in this study (n = 19). Values are presented as the mean ± standard deviation or median and range or frequency with percentages. For baseline comparison between groups, p-values of Mann-Whitney-U tests, independent sample t-tests or χ2-tests are reported as appropriate. Self-reported activity level: 0 = “not at all active”; 1 = “little active”; 2 = “moderate active”; 3 = “very active”
Cognitive training (n = 10) | Physical activity (n = 9) | p value | |
|---|---|---|---|
Age (years) | 62.5 ± 1.61 | 61.44 ± 2.4 | 0.356 |
Sex | 0.089 | ||
Male (%) | 9 (90%) | 5 (55.6%) | |
Female (%) | 1 (10%) | 4 (44.4%) | |
Years of education | 13.8 ± 0.8 (11.00–18.00) | 14.22 ± 1.12 (10.00–20.00) | 0.760 |
Age at PD symptom onset (years) | 51.9 ± 3.04 | 52.11 ± 2.51 | 0.939 |
Age at PD diagnosis (years) | 54.6 ± 2.0 | 53.11 ± 2.51 | 0.646 |
PD duration (months) | 96.5 ± 11.93 (48.00-188.00) | 97.33 ± 15.35 (44.00-163.00) | 0.905 |
Hoehn-Yahr stage | 0.303 | ||
1 (%) | 2 (20%) | 5 (55.6%) | |
2 (%) | 6 (60%) | 4 (44.4%) | |
2.5 (%) | 1 (10%) | 0 | |
3 (%) | 1 (10%) | 0 | |
4 (%) | 0 | 0 | |
UPDRS-III | 16 ± 0.2.17 | 13.11 ± 2.11 | 0.966 |
MoCA (max. 30 points) | 25.3 ± 0.33 | 26.22 ± 0.55 | 0.160 |
SCI – number of impaired cognitive domains (max. 6 points) | 3.4 ± 0.54 | 2.00 ± 0.44 | 0.065 |
BDI-II (max. 63 points) | 9.4 ± 1.56 | 6.22 ± 1.23 | 0.134 |
GSE (max. 40 points) | 27.6 ± 1.71 | 34.00 ± 0.94 | 0.006 |
PD-MCI subtype | |||
Single-domain PD-MCI (%) Multi-domain PD-MCI (%) | 0 | 0 | |
10 (100%) | 9 (100%) | ||
Physiotherapy at baseline | 8 (80%) | 7 (77.8%) | 0.906 |
Cognitive training previously | 1 (10%) | 1 (11.1%) | 0.937 |
Self-reported activity levelc | |||
not active at all | 0 | 0 | |
little active | 0 | 1 (11.1%) | |
moderate active | 7 (70% | 6 (66.7%) | |
very active | 3 (30%) | 2 (22.2%) | |