Table 1 Demographic characteristic, risk factors and thrombectomy parameters of the whole study population (N = 694) and the sample of the telephone survey (N = 138)

Age

74.0 ± 13.4

70.8 ± 14.7

U = 41803.000, Z = 2.360, p = 0.018^c

Sex—Female

361/694 (52.0%)

71/138 (51.4%)

0.015/0.903^a

Hypertension

609/694 (87.8%)

120/138 (87.0%)

0.067/0.795^a

Diabetes mellitus

130/694 (18.7%)

23/138 (16.7%)

0.327/0.567^a

Atrial fibrillation

330/694 (47.6%)

65/138 (47.1%)

0.009/0.923^a

Former stroke

188/694 (27.1%)

35/138 (25.4%)

0.175/0.676^a

Antiaggregant therapy on admission

187/694 (26.9%)

42/138 (30.4%)

0.665/0.415^a

Oral anticoagulation on admission (INR >  = 1.7) or (AntiXa >  = 0.4 IU/ml) or (thrombin time >  = 42 s)

41/694 (5.9%)

10/138 (7.2%)

0.358/0.549^a

Statin therapy on admission

162/694 (23.3%)

34/138 (24.6%)

0.125/0.724^a

Aetiology of stroke

 LAAS

107 (15.4%)

18 (13.0%)

4.344/0.227^a

 CES

302 (43.5%)

66 (47.8%)

 Other

29 (4.2%)

11 (8.0%)

 Cryptogenic stroke

177 (25.5%)

32 (23.2%)

 Missing

79 (11.4%)

11 (8.0%)

Event to door time

  < 1 h

75/694 (10.8%)

17/138 (12.3%)

 1–2 h

134/694 (19.3%)

31/138 (22.5%)

 2–3 h

109/694 (15.7%)

20/138 (14.5%)

 3–4 h

72/694 (10.4%)

14/138 (10.1%)

 4–5 h

44/694 (6.3%)

10/138 (7.2%)

 5–6 h

41/694 (5.9%)

3/138 (2.2%)

 6–24 h

80/694 (11.5%)

18/138 (13.0%)

 In house-stroke

33/694 (4.7%)

8/138 (5.8%)

 Unknown

95/694 (13.7%)

17/138 (12.3%)

5.903/0.750^a

 Intravenous thrombolysis

235/694 (33.9%)

55/138 (39.9%)

1.821/0.177^a

 Door to needle time

40.8 ± 20.3 min

41.8 ± 20.8 min

U = 6736.500, Z = 0.490, p = 0.624^c

(Median 36)

(Median 38)

 Door to groin time

98.4 ± 78.2 min

97.3 ± 62.1 min

U = 37307.500, Z = 0.084, p = 0.933^c

Median: 84

Median: 85

 Local intra-arterial thrombolysis

8/694 (1.2%)

3/138 (2.2%)

–^d

Severity indices on admission

 Modified Rankin Scale on admission

4.4 ± 0.9

4.2 ± 1.0

U = 39685.000, Z = 1.706, p = 0.088^c

Median: 5

Median: 5

 Modified Rankin Scale on admission

Score 0: 2 (0.3%)

Score 0: 1 (0.7%)

8.857/0.115^a

Score 1: 3 (0.4%)

Score 1: 0 (0%)

Score 2: 22 (3.2%)

Score 2: 4 (2.9%)

Score 3: 84 (12.1%)

Score 3: 28 (20.3%)

Score 4: 149 (21.5%)

Score 4: 25 (18.1%)

Score 5: 411 (59.2%)

Score 5: 71 (51.4%)

Missing: 23 (3.3%)

Missing: 9 (6.5%)

 Modified Rankin Scale at discharge

Score 0: 20 (2.9%)

Score 0: 5 (3.7%)

13.971/0.030^a

Score 1: 57 (8.4%)

Score 1: 19 (14.2%)

Score 2: 126 (18.6%)

Score 2: 28 (20.9%)

Score 3: 121 (17.8%)

Score 3: 29 (21.6%)

Score 4: 102 (15.0%)

Score 4: 18 (13.4%)

Score 5: 118 (17.4%)

Score 5: 24 (17.9%)

Score 6: 134 (19.8%)

Score 6: 11 (8.2%)

 Modified Rankin Scale at discharge

3.7 ± 1.7

3.1 ± 1.6

U = 37644.000, Z = 3.182, p = 0.001^c

Median: 4

Median: 3

 NIHSS on admission

15.6 ± 8.3

14.7 ± 7.3

U = 41300.500, Z = 1.212, p = 0.225^c

Median: 15

Median: 15

 NIHSS after 24 h

11.1 ± 8.2

9.9 ± 8.6

U = 24634.500, Z = 1.726, p = 0.084^c

Median: 9

Median: 7

 NIHSS at discharge

6.1 ± 10.8

13.3 ± 19.4

U = 33000.000, Z = 0.539, p = 0.645^c

Median: 3.5

Median: 5.5

Thrombectomy parameters

 Occluded target vessel

  M1

445/694 (64.1%)

89/138 (64.5%)

0.007/0.934^a

  M2

242/694 (34.9%)

48/138 (34.8%)

0.000/0.984^a

  M3

28/694 (4.0%)

6/138 (4.3%)

0.029/0.865^a

  M4

1/694 (0.1%)

1/138 (0.7%)

–^d

  ICA

176/694 (25.4%)

41/138 (29.7%)

1.130/0.288^a

  Basilar artery

61/694 (8.8%)

9/138 (6.5%)

0.768/0.381^a

  VA

12/694 (1.7%)

1/138 (0.7%)

–^d

  ACA

104/694 (15.0%)

19/138 (13.8%)

0.135/0.713^a

  PCA

38/694 (5.5%)

7/138 (5.1%)

0.037/0.848^a

  ACC

8/694 (1.2%)

1/138 (0.7%)

–^d

  SUCA

6/694 (0.9%)

2/138 (1.4%)

–^d

 Thrombectomy technique

  Single (vs. multiple) aspirations

308/694 (44.4%)

59/138 (42.8%)

0.352/0.553^a

  Stent retriever

435/694 (62.7%)

80/138 (58.0%)

1419/0.234^a

  Angioplasty

10/694 (1.4%)

3/138 (2.2%)

–^d

  Stentimplantation

116/694 (16.7%)

21/138 (15.2%)

0.199/0.655^a

 Result of thrombectomy

  TICI3

423/694 (61.0%)

91/138 (65.9%)

1.173/0.279^a

  TICI2b or TICI3

618/694 (89.0%)

128/138 (92.8%)

1.705/0.192^a

Complications

 Intracerebral bleeding

300/694 (43.2%)

56/138 (40.6%)

0.286/0.593^a

 Symptomatic bleeding

18/694 (2.6%)

1/138 (0.7%)

–^d

 Seizure

34/694 (4.9%)

4/138 (2.9%)

–^d

 Recurrent stroke/TIA within 72 h

6/694 (0.9%)

0/138 (0%)

–^d

 Infection within 72 h

355/694 (51.2%)

71/138 (51.4%)

0.004/0.949^a

 Delirium

35/694 (5.0%)

8/138 (5.8%)

0.133/0.715^a

MRI parameters

 MRI performed

107/694 (15.4%)

30/138 (21.7%)

3.344/0.067^a

 Volume of infarction

49.2 ± 56.7 ml

48.5 ± 48.7 ml

U = 1169.500, Z = 0.277, p = 0.781^c

 Degree of cerebral microangiopathy (Fazekas’ Score)

0: 20/102 (19.6%)

0: 11/29 (37.9%)

U = 1119.500, Z = 2.100, p = 0.036^c

1: 43/102 (42.2%)

1: 12/29 (41.4%)

2: 25/102 (24.5%)

2: 3/29 (10.3%)

3: 14/102 (14.7%)

3: 3/29 (10.3%)

 Fragmented infarction

91/103 (88.3%)

25/28 (89.3%)

0.019/0.890^a

 Fragmented infarction

Singular: 13/99 (13.1%)

Singular: 3/25 (12.0%)

U = 1225.500, Z = 0.078, p = 0.938^c

 ≥ 1 and < 5: 28/99 (28.3%)

 ≥ 1 and < 5: 9/25 (36.0%)

5—< 10: 26/99 (26.3%)

5—< 10: 4/25 (16.0%)

 ≥ 10: 32/99 (32.3%)

 ≥ 10: 9/25 (36.0%)

 Multi territorial infarction

59/103 (57.3%)

12/29 (41.4%)

2.302/0.129^a

 Brainstem or cerebellum involvement

45/103 (43.7%)

8/28 (28.6%)

2.089/0.148^a

 Involvement posterior circulation area

56/104 (53.8%)

11/29 (37.9%)

2.298/0.130^a

 Involvement anterior circulation area

67/104 (64.4%)

22/29 (75.9%)

1.340/0.247^a

 Telephone survey

 Interval after stroke

2.2 ± 1.2 years

(Median: 2.1 years)

 Modified Rankin Scale on admission

Score 0: 15 (10.9%)

Score 1: 23 (16.7%)

Score 2: 22 (15.9%)

Score 3: 19 (13.8%)

Score 4: 17 (12.3%)

Score 5: 7 (5.1%)

Missing: 35 (25.4%)

 Mobility

2.6 ± 1.3 (Median: 3)

 Self-care

2.3 ± 1.5 (Median: 2)

 Usual activities

2.7 ± 1.5 (Median: 3)

 Pain/discomfort

2.0 ± 1.1 (Median: 2)

 Anxiety/depression

2.4 ± 1.1 (Median: 2)

 EuroQol-visual analogue scales (EQ-VAS)

55.1 ± 25.2

 German EQ-5D-5L index

0.635 ± 0.318

 German level of care

0: 49/102 (48.0%)

1: 5/102 (4.9%)

2: 15/102 (14.7%)

3: 14 (13.7%)

4: 11 (10.8%)

5: 8 (7.8%)

Missing: 36

 Ongoing antiaggregant therapy

47/101 (46.5%)

 Ongoing oral anticoagulation

50/102 (49.0%)

 Ongoing statin therapy

75/101 (74.3%)

 Ongoing antihypertensive therapy

83/101 (82.2%)

 Ongoing antidepressive therapy

19/101 (18.8%)