Table 2 Multivariable analysis of factors associated with stroke

Left heart affected (mitral and/or aortic valve)

212 (82.5%)

95 (99.0%)

0.001

28.26

3.59-222.19

Extracerebral arterial embolic events

42 (16.3%)

36 (37.5%)

0.004

2.52

1.33–4.71

Acute liver failure

19 (7.4%)

19 (19.8%)

0.037

2.62

1.06–6.50

Dental focus of infection

17 (6.6%)

12 (12.5%)

0.019

3.12

1.21–8.12

Intracardiac medical devices other than artificial heart valves (e.g. MitraClip, ICD, pacemaker)

63 (24.5%)

11 (11.5%)

0.055

0.46

0.21–1.02

Congenital heart disease (e.g. bicuspid aortic valve)

26 (10.1%)

2 (2.1%)

0.049

0.20

0.04–0.99

Previous heart disease other than congenital heart disease

88 (34.2%)

23 (24.0%)

0.139

0.62

0.33–1.17

Acute renal failure requiring HD

49 (19.1%)

27 (28.1%)

0.949

0.98

0.49–1.96

Pathogen isolated in blood culture (no pathogen found = ref)

 Staphylococcus aureus

56 (21.8%)

35 (36.5%)

0.876

0.94

0.41–2.15

 Staphylococcus epidermidis

31 (12.1%)

6 (6.3%)

0.051

0.32

0.10-1.00

 Streptococcus mitis/oralis

19 (7.4%)

5 (5.2%)

0.137

0.36

0.10–1.38

 Enterococcus faecalis

27 (10.5%)

10 (10.4%)

0.610

0.77

0.28–2.14

 Other

97 (37.7%)

21 (21.9%)

0.006

0.31

0.14–0.72