Table 3 Sensitivity analysis of patients with IE affecting the left side of the heart

Extracerebral arterial embolic events

34 (16.0%)

35 (36.8%)

0.005

2.45

1.31–4.60

Acute liver failure

15 (7.1%)

18 (18.9%)

0.065

2.37

0.95–5.91

Dental focus of infection

0.016

3.30

1.25–8.72

Intracardiac medical devices other than artificial heart valves (e.g. MitraClip, ICD, pacemaker)

53 (25.0%)

10 (10.5%)

0.030

0.41

0.18–0.92

Congenital heart disease (e.g. bicuspid aortic valve)

15 (7.1%)

2 (2.1%)

0.050

0.20

0.04–0.99

Previous heart disease other than congenital heart disease

75 (35.4%)

23 (24.2%)

0.183

0.65

0.35–1.23

Acute renal failure requiring HD

39 (18.4%)

26 (27.4%)

0.891

0.95

0.47–1.92

Pathogen isolated in blood culture (no pathogen found = ref)

 Staphylococcus aureus

39 (18.4)

34 (36.2%)

0.850

0.92

0.40–2.13

 Staphylococcus epidermidis

28 (13.2%)

6 (6.4%)

0.057

0.32

0.10–1.03

 Streptococcus mitis/oralis

13 (6.1%)

5 (5.3%)

0.128

0.35

0.09–1.35

 Enterococcus faecalis

24 (11.3%)

10 (10.6%)

0.609

0.77

0.27–2.14

 Other

85 (40.1%)

20 (21.3%)

0.006

0.31

0.13–0.71